Assisted Hatching: Facilitation of Implantation of the Embryo
An embryo has a protective layer around it (zona pellucida) in early days of development. The process of implantation of the embryo begins on the fifth or sixth day after fertilization, when the embryo leaves its protective shell, zona pellucida disappears and the embryo cells get into direct contact with the uterine lining cells. This also causes elimination of a mechanical barrier which would impede further growth of the embryo.
Problems with recurrent implantation failure may be caused by the embryo’s inability to “abandon” its protective shell or by the changes in the protective layer. In such cases, we perform the assisted hatching. In this technique we disrupt the hard shell of the embryo by laser or by a special needle, just before the transfer. Thus we make it easier for it to attach to the uterine wall.
For what cases is assisted hatching appropriate:
- for older women who have eggs with a harder shell
- for repeated implantation failure
- for frozen embryos
It is important for assisted hatching to be carried out by an experienced professional. All our embryologists have completed years of practice and professional education at top universities. You can see for yourself on this page Europe IVF International about employees.
Experience of foreign experts
The method was discovered in early 90s by Dr. Jacques Cohen of Cornell Medical College in New York. Suitability of the method for couples with repeated implantation failure was demonstrated for example in this Brazilian study.
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